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Int J Oncol 47(6):22262232 Kolonel LN, Hankin JH, Whittemore AS, Wu AH, Gallagher RP, Wilkens LR, John EM, Howe GR, Dreon DM, West DW, Paffenbarger RS Jr (2000) Vegetables, fruits, legumes and prostate cancer: a multiethnic case-control study

Int J Dev Neurosci Off J Int Soc Dev Neurosci (2013) 31(6):45262

In 90% of hereditary cases of ALS, patients have mutations in the superoxide dismutase 1 (SOD1) enzyme which converts O 2 to H 2 O 2 and O 2 to protect cells from ROS, and is directly associated with oxidative stress and inflammation [180]

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The advent of convenient laboratory assays revealed mild to moderate elevation of blood homocysteine concentrations in association with vitamin insufficiencies (i.e., folate, vitamin B12, vitamin B6, and riboflavin), several diseases and disorders, some pharmaceuticals, and lifestyle factors (7)