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However, when your body has more histamine than it can efficiently break down, it can lead to symptoms like:( 1 ) Skin problems like itching, rashes, and eczema Irregular and/or painful periods Allergic asthma and difficulty breathing Motion sickness (boat, car, amusement park) Runny nose, sneezing, nosebleeds, or red face Bloating, excessive gas, abdominal cramping, or nausea Food intolerances and sensitivities Dizziness Feelings of unease Headaches or migraines Difficulty falling asleep Pregnancy complications Acid reflux, stomach and digestive problems Heart palpitations The Two Main Histamine Genes Genes make enzymes

R.et al (2006)

The tolerability gap may be less significant in practice than the raw nausea percentages suggest

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10.3389/fncel.2020.609947 27 CavacciniA.DurkeeC.KofujiP.ToniniR.AraqueA

Conclusion: In this large VHA cohort of NAFLD patients referred to the MOVE