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Reprod Fertil 4(1):e220070

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Evidence of lipid peroxidation by increased levels of malondialdehyde and other such substances such as 8-isoprostane and thiobarbarbituric acid-reactive substance levels is one of the primary means by which researchers have associated oxidative processes with an overall decrease of cellular function

The fact that the oxidation state of the active site cysteine of Prx can be transferred to other proteins allows Prx to function as a sensor of H 2 O 2 (Rhee et al., 2012)

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