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Symptomatologic improvement was greater in patients younger than 6 years of age as compared to those who began supplementation at an older age, though, this study was a case series of 20 patients, further randomized controlled trials are needed

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Nox4 is critical for hypoxia-inducible factor 2-alpha transcriptional activity in von Hippel-Lindau-deficient renal cell carcinoma

doi: 10.1007/s10072-006-0599-6

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