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But, it should be noted that LC-50 values are markedly affected by surrounding water temperature, pH, Eh, organic load and phosphate concentrations, suspended solids and presence of other substances and toxicants (Kumari et al., 2017)

In neurodegenerative diseases like Alzheimers and Parkinsons, antioxidants may help protect neurons from oxidative damage and slow disease progression [199]

doi: 10.1136/gutjnl-2018-318126 30 KalisperatiPSpanouEPaterasISKorkolopoulouPVarvarigouAKaravokyrosIet al

The CTLA-4 antibody, Ipilimumab, binds to CTLA-4 on effector T cells, thereby alleviating inhibition and exerting its ADCC function to eliminate Tregs