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UPS participates in both pro- and anti-fibrotic processes through the degradation of several TGF-/Smad signaling pathway constituents

It contains various bioactive substances, such as polysaccharides, phenolic compounds, fatty acids, carotenoids, and tocopherols

This suggests that the cause of many cancers is largely environmental that is, down to factors such as diet, lifestyle and exposure to toxic chemicals

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PLoS One 19:e0299042 Chen Y, Huang L, Zhang H, Diao X, Zhao S, Zhou W (2017) Reduction in autophagy by (-)-epigallocatechin-3-gallate (EGCG): a potential mechanism of prevention of mitochondrial dysfunction after subarachnoid hemorrhage