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Dose-dependent nausea was the most common complaint

32 The Wnt signaling network can be separated into the -catenin-dependent Wnt signaling pathway and the -catenin-independent Wnt signaling pathway.2 The primary activators of the former canonical pathway are Wnt2b, Wnt3, Wnt3a, Wnt8a, Wnt8b, Wnt9a, and Wnt10b

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