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Mechanisms of disease: the role of intestinal barrier function in the pathogenesis of gastrointestinal autoimmune diseases

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Thereby, the expression of several adhesion molecules and cytokine secretion was altered in bone marrow stroma cells under overload conditions impairing their capacity to support hematopoietic cells growth (105, 107)

In oral squamous cell carcinoma, RECK is often downregulated due to promoter hypermethylation or genetic changes, leading to an increased MMP activity, which enhances tumor invasion and metastasis (32)