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The main differences between adult and pediatric patients are as follows: In the pediatric population, there is a lack of information, as there are no randomized controlled trials (RCTs), and most studies conducted are observational in nature

10.1016/j.bcp.2005.11.003 Biochem

Transition to heat therapy after the initial inflammatory phase , as heat helps relax muscles and improve blood flow

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However, the brain is highly susceptible to oxidative damage due to its high oxygen consumption and limited antioxidant defenses (Sies et al., 2017)

Similarly, the mean per capita daily dietary intake of selenium was estimated at 87.7 g, vitamin B 12 at 0.68 g, vitamin C at 43.1 mg, zinc at 9.8 mg and vitamin A at 162.5 g (Supplementary Figure 2)