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Under hypoxic conditions, cells activate the hypoxia signaling pathway, which is mainly mediated by the hypoxia-inducible factors (HIFs), to induce a series of cellular responses to help cells to adapt to or escape from the hypoxic environment [19,20,21]

Human rhodopsin is a G-protein coupled receptor and an integral membrane protein of the light-absorbing molecules that mediate vision

After homogenization, the samples were placed inside the refrigerator for 15 min to aid the precipitation and then centrifuged at 10,000 rpm for 15 min at 4 C to precipitate out the protein The supernatant was used to determine 5-HT and 5-HIAA levels in the cerebral cortex and midbrain samples

Therapeutic effect and molecular mechanism of Salvia miltiorrhiza on rats with acute brain injury after carbon monoxide poisoning based on the strategy of internet pharmacology

Scientific References Seiwerth, S., et al