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Jia L, Zhu M, Kong C, et al

Although the rat GCLM promoter lacks NFB binding site, NFB can indirectly enhance GCLM expression by activating AP-1 (Yang et al., 2005b)

Polyunsaturated fatty acids (PUFAs), the substrate of ALOX15, can subsequently be complexed with free PEBP1 to produce PUFA-PE

Serum IGF-1 is low, but systemic IGF-1, for example in muscles, may be high

n = 12)

In conclusion, phenylalanine, X-12,100 hydroxytryptophan, and 5-hydroxyproline have a causal relationship with the occurrence of PD and may be potential early screening biomarkers and blocking targets