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The JAK family (JAK1, JAK2, JAK3, TYK2) binds non-covalently to cytokine receptors, while STATs, as JAK substrates, couple with the tyrosine phosphorylation signaling pathway [117]

Healthcare professionals, including toxicologists, dietitians, and medical practitioners, monitor and prescribe this treatment to ensure safety and effectiveness

10.1186/s13567-018-0562-6 84

doi: 10.1016/S0140-6736(96)07493-4

Inhibition of IFNs and ISGs is a tactic used by several viruses to evade host antiviral responses [47], and SARS-CoV-2-mediated IFNs and ISGs dysregulation appears to be an important strategy used by this virus to replicate and disrupt immune homeostasis

Therefore, it is necessary to closely modulate fatty acid metabolism to avoid the toxicity noted in the cell death pathways, such as ferroptosis