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Moreover, distinct cytokine signatures have been associated with varying severity levels of ME/CFS, where higher levels of plasma pro-inflammatory cytokines, such as colony-stimulating factor 2 (CSF2), correlate with increased physical and fatigue symptoms in these patients (Giloteaux et al., 2023)

Second, GST also functions as an MAPK-pathway inhibitor to prevent tumor-cell apoptosis

(A, B) Cell viability assay in U-2 OS cells treated with gradient concentrations of PAF C16 (A) or PAF C18 (C) for 12 hours

[Abstract]2022 Nov 30;14(47):52643-52658

Accumulating evidence would also suggest that insufficient IGF-I levels play a role in vascular diseases such as atherosclerosis and restenosis[155], what will be discussed in further sections (cardiovascular diseases)