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A product of lipid peroxidation, 4-hydroxynonenal, has been shown to induce apoptosis in neuroblastoma cells by elevating the levels of p53, p63 and p73 and p63 staining has been used as a marker for prostatic adenocarcinoma where lack of p63 staining indicates malignant prostatic adenocarcinoma [14,18]

Four DEGs, including Azgp1, CD3 Delta Subunit Of T-Cell Receptor Complex (Cd3d), CD8 Subunit Alpha (Cd8a), and cytochrome P450 family 2 subfamily d polypeptide 10 (Cyp2d10), were also identified among the taurine-treated group, the model group, and the control group from the RNA-seq data (Fig

Laurent TC, Moore EC, Reichard P

Minimum (min) and maximum (max) distances with mean and standard deviations (sd) between Glu614 and Pro626 of the rigid part of the pocket and certain residues of the flexible loop region are given in

Also, miR-26a is reported to be major regulator in fatty acid and sterol metabolism

To test whether CCL2 is mediating the chemotactic effects of oxalate, we knocked down CCL2 in HepG2 cells using siRNA (siCCL2) as confirmed by qRTPCR (Extended Data Fig