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Their results revealed that decreasing NNMT expression in primary hepatocytes led to a reduction in the expression of phosphoenolpyruvate carboxykinase 1 (Pck1) and glucose-6-phosphatase (G6pc), resulting in decreased glucose output

This helps with both normal mitochondria degradation as well as mitochondrial dysfunction-related conditions such as heart failure, ischemia-reperfusion injury, neurodegenerative diseases, and metabolic disorders

[2] Ramsden DB, Waring RH, Barlow DJ, et al

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