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Due to its increasing recreational use and potential risks, the United States classified MDMA as a Schedule I controlled substance in 1985, making it illegal for most uses, according to the MDMA (Ecstasy) Fast Facts published by the National Drug Intelligence Center

this is known as iron addiction [34]

Data availability No data with mandated deposition was generated as a result of this study

Furthermore, mucositis-induced ulcerated lesions severely compromised oral hygiene in the majority of patients, even those who had received prior dental care, as the therapy primarily focused on extractions and dental restorations, which had a limited impact on the biofilm and hygiene conditions

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Chunhong Li, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers