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10.1097/00000542-200405000-00020 Anesthesiology 42 FreoU.OriC

Through genome-wide CRISPR screening, several HIF pathway genes were shown to be essential for ferroptosis in clear-cell renal cell carcinoma (ccRCC) cells

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SAG is like wearing an invisibility cloak : it does not alter GSH itself but covers the vulnerable thiol group with an acetyl cloak, allowing it to cross cell membranes undetected