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T 4 , thyroxine (3,5,3,5-tetraiodothyronine), is produced by follicular cells of the thyroid gland

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The objective of the present study was to determine the effect of chronic exposure to 3MC, a major PAH, on the transsulfuration pathway using targeted metabolomics analysis, aiming to provide novel insights into the mechanism through which 3MC affects intracellular GSH levels and renders cells vulnerable to a second insult of oxidative stress

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Treatment of plasma with HOCl led to the rapid depletion of thiol groups and methionine residues in the proteins, demonstrating the potential of plasma proteins, particularly HSA, to effectively scavenge HOCl [316]

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