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This HexaPro antigen was used in a regimen termed prime and spike, in which a priming dose was administered intramuscularly to induce peripheral immune memory and a boosting dose was administered intranasally to expand and recruit spike-specific T and B cells to the mucosa [167]

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By inhibiting NNMT, 5-Amino-1MQ effectively disrupts this process, leading to a reduction in fat storage and promoting increased fat oxidation

37 However, peptides derived from mammalian tissues and synthetic sources often encounter pharmacokinetic limitations, including rapid degradation, short plasma half-life, and poor oral bioavailability

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