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Description

Ion channels in osteoarthritis: emerging roles and potential targets

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The ACSL4 inhibitor rosiglitazone improves kidney function in DKD mice and reduces the lipid peroxidation product and iron content, and these effects are correlated with attenuated ferroptosis (23)

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At the same time, VK reductase Ferroptosis Inhibitory Protein 1 (FSP1) inhibits ferroptosis by reducing VK to VKH2 and prevents lipid peroxidation by depleting NAD(P)H (Li et al., 2023)

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Quality assurance is essential given the variable regulation of the supplement market

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