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FDA approved : For the management of moderately severe to severe essential hypertension and in uncomplicated cases of malignant hypertension

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10.1016/j.ejphar.2017.01.013 116 ShankerG.Sorci-ThomasM.AdamsM

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Insulin promotes glucose uptake into these tissues by triggering a protein phosphorylation signalling cascade, which converges on multiple trafficking processes to deliver the glucose transporter GLUT4 to the cell surface