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Phenytoin is a potent inducer of CYP 2C9, 2C19, and 3A4, resulting in innumerable drug-drug interactions.(34300194) interactions between phenytoin and valproate Effect on phenytoin: Valproate inhibits CYP2C9, resulting in the accumulation of phenytoin

Vitamin B12 deficiency may occur in between 40% to 80% of the vegetarian population who are not also consuming a vitamin B12 supplement.In Hong Kong and India, vitamin B12 deficiency has been found in roughly 80% of the vegan population as well

Yogosawa, S., Mizutani, S., Ogawa, Y

This is believed to result from the increased blood volume induced by methylcobalamin

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