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The limited impact of METTL3 overexpression on the proteome or transcriptome may result from a combination of factors, including the dynamic equilibrium of m6A modification, the complex regulation of mRNA stability and translation, and cellular compensation mechanisms [38]

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RNR catalyzes the reduction of ribonucleotides to deoxyribonucleotides

However, it is worth noting that, at present, there is a lack of relevant research on this subject