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Jaka Vukojevi, Marija Milavi, Darko Perovi, Spomenko Ili, Andrea Zemba ili, Nataa uran, Sanja trbe, Zoran Zorii, Igor Filipi, Petrana Brei, Sven Seiverth, & Predrag Sikiri

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The peptide's neuroprotective mechanisms involve activation of the PI3K/AKT signaling pathway, which plays crucial roles in neuronal survival, protein synthesis, and protection against apoptosis

Cagrilintide is used as a research tool in this context because long acting amylin analogues can support extended timecourse experiments that examine signaling persistence, pathway engagement kinetics, and differences across receptor complex variants