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Z-score correlated negatively with disease duration (r = -0.354, p = 0.037), diagnostic delay (r = -0.356, p = 0.042), and hospitalization duration (r = -0.601,p = 0.008)

Supplementary Table S1)

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2.3.2 Dysfunction of innate immune cells in MS Innate immune cells within the CNS are key drivers and modulators of damage in MS