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10.1111/j.1365-2664.2012.02212.x J

Disruptions circadian rhythmicity in core clock gene expression patterns has vast implications contributing to increased stroke risk and impaired recovery

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Another microbial-derived metabolite, Urolithin A, a coumarin, is found in plasma of healthy adults and derived from ellagitannins found in pomegranates, walnuts, and berries and has both protective effects on BBB integrity pre stroke and therapeutic effects post stroke [153]