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This adaptive response is similar to that which occurs due to high dietary K + intake in normal subjects 103

This is supported by findings in bone marrow-derived macrophages, where treatment with RBCs to induce EP resulted in a marked increase in HO-1 expression (approximately 10-fold) (87)

Given that NACA was able to counteract the effects of the ACOX1 gain-of-function mutation, antioxidant treatment was considered for patient#1 during a severe disease flare

These properties are relevant given the established role of HGH in cartilage growth and repair through the local stimulation of IGF-1

NUTRACEUTICAL Not for medicinal use

echo time [TE] = 2.28 ms