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10.1038/s41392-023-01502-8 124 LiZ.ZhangW.DuanY.NiuY.ChenY.LiuX.et al (2023b)

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So the uncomfortable conclusion remains: we do not yet have the kind of human trial evidence that should be driving widespread clinical adoption for injury recovery

During the mean observation period of 3.3 years, semaglutide at 2.4 mg per week resulted in a mean weight loss of 9.39% from baseline and a 20% reduction in the risk of MACE (HR 0.80, 95% CI 0.720.90), especially a 28% reduction in the risk of myocardial infarction (HR 0.72, 95% CI 0.610.85), compared with that in the placebo group

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