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5-Methyl THF serves as a methyl donor in the vitamin B 12 -dependent reactions catalyzed by methionine synthase, which remethylates homocysteine to methionine, regenerating THF

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Additionally, B12 is involved in reducing homocysteine levels, an amino acid linked to higher stress and anxiety

Also, those who have anemia or are vegetarian or vegan will want to consider a B12 regimen, as vegetable-based diets generally dont contain the amount of B12 that you need to thrive

Even though the NICE Guideline says that patients may need more frequent injections GPs are still largely ignoring or unaware of this guidance