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Taking advantage of distinct electrophoretic mobilities of wild-type and mutant SOD1 proteins (G85R and L126Z), furthermore, wild-type human SOD1 was found to accumulate as detergent-insoluble aggregates with the mutant proteins in transgenic mice [29, 31, 33, 34], while the interactions in the aggregates would not be simply a co-assembly of mutant and wild-type proteins [33]

Unlike other B12 types, it binds well to blood proteins, allowing it to stay active for several days to weeks after administration

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Taking into consideration of inconsistent experimental results currently, further research is needed to ascertain whether DJ-1 may be used as a salivary biomarker for the diagnosis of PD