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These deposits disrupt the structure and function of cells 9

This might be attributed to localisation of the inflammation to the intestine in CD causing alteration of the DMET protein abundances

Exp Toxicol Pathol 59(6):415423

Key bottlenecks, including the lack of standardized protocols, limited inter-laboratory harmonization, insufficient regulatory frameworks for biomarker validation, and challenges in biological interpretation, must be systematically addressed

Symptoms for a given percentage of methemoglobin are generally more severe in a patient who has some pre-existing condition (e.g

implications for mutagenesis in an infectious strain background