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This condition classically manifests with severe hypertriglyceridemia, recurrent acute pancreatitis, hepatosplenomegaly, and eruptive skin xanthomas

While ROS display varying reactivities toward different targets, they share the ability to damage cells by oxidizing proteins, lipids and DNA

Bamagous GA, Al Ghamdi SS, Ibrahim IA, Mahfoz AM, Afify MA, Alsugoor MH, Shammah AA, Arulselvan P, Rengarajan T

This upregulates downstream antioxidant enzymes (e.g., HO-1, NQO1) and maintains intracellular GSH levels, reducing ROS accumulation and enhancing neuronal resistance to A toxicity (251)

Other compound-related toxic lesions in rats were seen in the liver, kidney and testes

In recent years, ovarian cancer has been observed in younger patients, and the degree of harm has also increased [1, 2]