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PT-141 PT-141 is a non-selective melanocortin receptor agonist that treats men with erectile dysfunction and women with sexual arousal disorders

In allergic DILI, the drug or its intermediate metabolites become haptens that bind to proteins in hepatocytes and acquire antigenicity, triggering an immune response that leads to hepatocyte destruction

Other relevant group of agents tested in NASH include the lipid-lowering drugs (e.g

They also help by reducing blood lactate during exercise

In cancer research, a recent focus lies on the interplay between energy metabolism and histone modifications, particularly those involving lactylation, palmitoylation, succinylation, and others

Hence, we hypothesized that GSTA4 might reduce cisplatin ototoxicity by removing 4-HNE from cochlear cells in female mice