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John Harris, a dermatologist at University of Massachusetts-Worcester, had shown that tofacitinib keeps the immune system from attacking the skin cells that manufacture melanin pigment (color), and light stimulates pigment-making cells to restore color to the skin

This can denature (destroy) the peptide at the air-liquid interface

Various animal models demonstrates that FMT effectively mitigates intestinal oxidative stress by lowering the production of ROS (237)

The purified protein fraction was concentrated using an Amicon centrifugal filter unit (Millipore, Billerica, MA, USA)

ATP restoration experiments revealed that synthesis of new AMP is essential for the rapid restoration of normal ATP levels in ATP-depleted astrocytes and that this AMP synthesis via the purine salvage pathway requires an adenine precursor, a substrate that is efficiently metabolized to provide the energy for efficient ATP regeneration from ADP [60] as well as a suitable substrate that provides the ribose phosphate needed for AMP synthesis [241]

Besides, biochemical, pathological, and immunohistochemical assessments were performed to evaluate if CCM could afford therapeutic effectiveness against GEN or NaS accompanied ototoxic effect