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In this context, it is reported that the I3C is rapidly absorbed and distributed into different tissues and fluids such as the liver, kidney, heart, lung, brain, and plasma after oral administration of 250 mg/kg to mice, detecting the highest concentrations in the liver and kidney

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Additionally, alpha-synuclein a protein that clumps in the brains of all people with Parkinsons has been found in several locations outside the brain, including the nerves controlling the intestines

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Firstly, the metabolic enzymes implicated in the peroxidation of phospholipids, LOXs and POR, require iron for catalysis

RLIP76: A Target for kidney cancer therapy