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Coupled Transcription-Translation in Prokaryotic Cell-Free Systems

Activation of these receptors by fluoxetine triggers several signalling cascades

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While in vitro experiments yield detailed information on single aspects, in vivo studies with human volunteers or patients allow for the determination of typical pharmacokinetic parameters, such as maximum concentrations in serum or plasma (c max ), time of peak concentrations (t max ), area under the curve (AUC), half-live (t) and other elimination characteristics