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395 The loss of double-strand repair pathway due to BRCA1 or BRCA2 mutations renders cancer cells more dependent on the PARPs-mediated repair, and more sensitive to PARP inhibition, raising a possibility of a wider application of PARPi in cancer therapy

Zhou B, Yu P, Lin M-Y et al (2016) Facilitation of axon regeneration by enhancing mitochondrial transport and rescuing energy deficits

In contrast, at more mature synapses, the calcium nanodomains defined by calcium influx via only NMDARs and VGCCs seem to be sufficient for bAP-induced site-specific local BDNF release from dendrites

Triggers of IL-1 production have been observed in a number of different stimuli, such as sulfur mustard, nickel, contact allergens or superantigens 36 IL-1 stimulates further release of secondary mediators, including IL-8

However, other observations suggest that the residual CD38 low/- NK population displays a high proliferative potential and functional activity

Cottage Cheese: Cottage cheese provides approximately 1.0 mcg of B12 per cup a useful contribution from a food that is often included in high-protein dietary patterns