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Description

Bcl-2 / Bax ratio A molecular "survival score." Bcl-2 is an anti-apoptotic protein that protects cells from death

NDC: 70069-0172-10

GHR Signaling Pathway to IGF1 Gene Transcription The important cell signaling steps associated with GH stimulated IGF1 gene activation, transcription and IGF-I production are detailed in the Endotext chapter Normal Physiology of Growth Hormone in Adults

Most information comes from animal models and involves GH signaling in the liver, but in mouse adipose tissue GHR KO downregulates beta-3 adrenergic receptor expression and inhibits lipolysis (73)