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Alterations in gene expression may significantly influence skin aging by affecting metabolic pathways within skin cells (Schaum et al., 2020

A critical appraisal of the protective activity of polyphenolic antioxidants against iatrogenic effects of anticancer chemotherapeutics

For instance, during mitochondrial respiration, the electron transport chain occasionally leaks electrons that react with molecular oxygen to form superoxide radicals (O2) [22]

This AT-specific ER stress directly impairs insulin signaling by promoting c-Jun N-terminal kinase (JNK)-mediated serine phosphorylation of insulin receptor substrate (IRS-1), reducing glucose uptake capacity by up to 60% (101)

These bifunctional nanomaterials encompass inorganic nanomaterials, organic polymer materials, and photosensitizers