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The trial enrolled 300 obese subjects (BMI 27-35 kg/m) across multiple centers and randomized them to AOD-9604 (3 mg subcutaneous injection once or twice daily) or placebo for 12 weeks

Abeta interactions with copper and zinc can control the aggregation state of Abeta

Silent information regulator 2 (Sir2) and Forkhead box O (FOXO) complement mitochondrial dysfunction and dopaminergic neuron loss in Drosophila PTEN-induced kinase 1 (PINK1) null mutant

doi: 10.3390/ijms21061986 280

Synthetic and analytical strategies for the quantification of phenyl-gamma-valerolactone conjugated metabolites in human urine