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Bottom line : If you wanna get serious about retinoids, RP is not your ingredient (retinol or tretinoin is!)

R.Van Den BoschL.ZetterbergH.HoltzmanD

High melatonin concentrations in third ventricular cerebrospinal fluid are not due to Galen vein blood recirculating through the choroid plexus

Unexpectedly, this was attributed to a non-canonical transaminase pathway, independent from canonical -KG-dependent immunometabolism (Merlin et al., 2021)