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10.1007/s10571-016-0452-2 Cell

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In this review, we discuss the regulatory network of ferroptosis, describe the crosstalk between ferroptosis and HCC-related signaling pathways, and elucidate the potential role of ferroptosis in various treatment modalities for HCC, such as systemic therapy, radiotherapy, immunotherapy, interventional therapy and nanotherapy, and applications in the diagnosis and prognosis of HCC, to provide a theoretical basis for the diagnosis and treatment of HCC to effectively improve the survival of HCC patients

This may be difficult to achieve from diet or tablet supplements alone, due to the difficult nature of B12 absorption

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10.1016/j.chom.2023.05.002 74