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Ion levels including sodium, potassium, and calcium, all of which modulate RBC function and affect hemolysis, are known to change with storage 56

Indeed, expression of the sortilin ectodomain, which corresponds to the domain released after shedding, impairs lysosomal targeting and degradation of BDNF (Evans et al., 2011)

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10.1007/s13577-022-00682-9 48 ZhangD

Paradoxically, mice lacking gamma-glutamyl transpeptidase (GGT)an enzyme essential for GSH degradationdeveloped milder fibrosis following BLM exposure [126]