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Proteasome inhibition induces DNA damage and reorganizes nuclear architecture and protein synthesis machinery in sensory ganglion neurons

Antioxidants and exercise performance: with a focus on vitamin E and C supplementation

A diagnosis of primary carnitine deficiency requires that serum, red cell and/or tissue carnitine levels be low and that the patient does not have a primary defect in fatty acid or organic acid oxidation (see CLINICAL PHARMACOLOGY)

Foods rich in Vitamin C, such as citrus fruits, peppers, broccoli, and strawberries, can help restore healthy levels

The carnitine pool as multidisease biomarker, crosstalk mediator, and therapeutic target The differences in the composition and levels of the carnitine pool in different organs reflect their unique metabolic states and health conditions, carnitine/acylcarnitine have the potential to serve as biomarkers for the occurrence and development of a variety of diseases

Further mechanistic studies are also needed to isolate and characterize the bioactive molecules responsible for the observed inhibition, for example, through metabolomics and in vitro assays with purified TMA lyase (CutC/D) to clarify inhibition kinetics