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This extraordinary sensitivity is mediated by the activation of the mechanosensitive transient receptor potential cation channel subfamily M member 7 (TRPM7), which in turn triggers calcium ions (Ca 2+ ) influx, thereby promoting a thicker actomyosin cortex [50]

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In addition, the long-term effects of autologous fibroblasts and fibrosis on native NP tissue structure and NP cell populations will also need to be evaluated

Barrett, Joseph Coupet, Boyd Harrison, Hossein, Mazandarani SN, Menelas N