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We found that administration of BSO to established PDX tumors with high ACTL6A expression decreased the total GSH level but exerted no impact on the glutamine or glutamate level (Fig

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doi:10.1016/j.toxlet.2009.12.004 Tirmenstein MA, Nicholls-Grzemski FA, Zhang JG, Fariss MW (2000) Glutathione depletion and the production of reactive oxygen species in isolated hepatocyte suspensions

Zinc also reduces oxidative stress by participating in the synthesis of antioxidant enzymes and acts as a catalyzer of enzymes, taking part in lipid, carbohydrate, and protein metabolism

Redox proteomic identification of 4-Hydroxy-2-nonenal-modified brain proteins in amnestic mild cognitive impairment: insight into the role of lipid peroxidation in the progression and pathogenesis of Alzheimers disease