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Oleaginous yeasts: promising platforms for the production of oleochemicals and biofuels

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10.1038/nature16549 Nature 84 SoghomonianJ.MartinD

The extensive production of ammonia by peripheral tissue or glutamate dehydrogenase is not allowed because of the highly toxic effects of circulating ammonia in cells

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Nineteen different kavalactones have been identified [15] which can be metabolized in the liver by cytochrome P450 enzymes (CYP450) [16]