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Pharmacological inhibition of FSP1 disrupts CoQ10 regeneration, increasing lipid peroxidation and sensitizing glioblastoma cells to ferroptosis inducers

& Hurst, R

Antioxid Redox Signal 33:498516 Ogata FT, Simes Sato AY, Coppo L et al (2022) Thiol-based antioxidants and the epithelial/mesenchymal transition in cancer

Cognitive function was evaluated with the Brief Assessment of Cognition in Schizophrenia (BACS) battery of cognitive tests, which allows a measurement of global cognitive function across six domains: verbal memory with word list learning task, working memory with digit sequencing task, verbal fluency with controlled oral word association task, motor function with token motor task, attention and speed of information processing with symbol coding task and executive functions with Tower of London task

In addition, sections prepared from formalin-fixed liver (University of Harbin, Harbin, China), breast (Auckland Tissue Biobank, University of Auckland) and lung (Department of Anatomy and Medical Imaging, University of Auckland) carcinoma were tested as positive controls for GPX1 immunostaining

This tripeptide not only serves as a guardian against oxidative stress but also acts as a regulator, disrupting the melanin synthesis process at its core