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Among these, SPIONs represent a distinct class of nanomaterials composed of magnetite (Fe 3 O 4 ) or maghemite (-Fe 2 O 3 ), exhibiting a solid spherical shape

Peptidase therapy also reduced the infiltration of the pancreas by MPO neutrophils and F4/80 monocytes (120), we believe these data support future CXCR2-based therapeutic interventions

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Hence, some drug development focuses on peripherally restricted KOR agonists to retain analgesic efficacy with a more favorable adverse effect [61]