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In vitro, we found that in PSCs, high ROS accumulation attributed to high glucose was associated with PSC activation, which was characterized by increased expression of -SMA, accelerated migration, and increased synthesis of ECM proteins such as collagen I, all of which were rescued by GSH treatment

Stroke 28:17441748 Schwenke DC, Carew TE (1989) Initiation of atherosclerotic lesions in cholesterol-fed rabbits

Epithelial transglutaminase 2 is needed for T cell interleukin-17 production and subsequent pulmonary inflammation and fibrosis in bleomycin-treated mice